Il34 Mouse Gene Knockout Kit (CRISPR)
Specifications
| Product Data | |
| Format | 2 gRNA vectors, 1 mBFP-Neo donor, 1 scramble control |
|---|---|
| Vector | mBFP-Neo |
| Target Symbol | Il34 |
| Locus ID | 76527 |
| Components |
KN308286G1, Il34 gRNA vector 1 in pCas-Guide CRISPR vector KN308286G2, Il34 gRNA vector 2 in pCas-Guide CRISPR vector KN308286BND, donor DNA containing left and right homologous arms and mBFP-Neo functional cassette. GE100003, scramble sequence in pCas-Guide vector |
| OTI Disclaimer | These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process. |
| Reference Data | |
| RefSeq | NM_001135100, NM_029646 |
| UniProt ID | Q8R1R4 |
| Synonyms | 2010004A03Rik; AI593503 |
| Summary | Cytokine that promotes the proliferation, survival and differentiation of monocytes and macrophages. Promotes the release of proinflammatory chemokines, and thereby plays an important role in innate immunity and in inflammatory processes. Plays an important role in the regulation of osteoclast proliferation and differentiation, and in the regulation of bone resorption. Signaling via CSF1R and its downstream effectors stimulates phosphorylation of MAPK1/ERK2 AND MAPK3/ERK1 (By similarity).UniProtKB/Swiss-Prot Function |
| Shipping | Ambient |
Reviews
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| GA210535 | Il34 CRISPRa kit - CRISPR gene activation of mouse interleukin 34 | 1 kit |
$1,657.00
|
|
| KN308286 | Il34 - mouse gene knockout kit via CRISPR, HDR mediated | 1 kit |
$1,657.00
|
|
| KN308286LP | Il34 - mouse gene knockout kit via CRISPR, HDR mediated | 1 kit |
$1,657.00
|
|
| KN308286RB | Il34 - mouse gene knockout kit via CRISPR, HDR mediated | 1 kit |
$1,657.00
|
|
| KN508286 | Il34 - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. | 1 kit |
$1,657.00
|
|
Citations
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