Il2 Mouse Gene Knockout Kit (CRISPR)

CAT#: KN308264

Il2 - mouse gene knockout kit via CRISPR, HDR mediated

Product images

Specifications

Product Data

• Format: 2 gRNA vectors, 1 GFP-puro donor, 1 scramble control
• Donor DNA: GFP-puro
• Symbol: Il2
• Locus ID: 16183
• Kit Components:

  KN308264G1, Il2 gRNA vector 1 in pCas-Guide CRISPR vector

  KN308264G2, Il2 gRNA vector 2 in pCas-Guide CRISPR vector

  KN308264-D, donor DNA containing left and right homologous arms and GFP-puro functional cassette.

  GE100003, scramble sequence in pCas-Guide vector

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.

Reference Data

• RefSeq: NM_008366
• UniProt ID: P04351
• Synonyms: Il-2
• Summary: Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Can stimulate B-cells, monocytes, lymphokine-activated killer cells, natural killer cells, and glioma cells.[UniProtKB/Swiss-Prot Function]