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Esr1 Mouse Gene Knockout Kit (CRISPR)

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SKU
KN305380LP
Esr1 - mouse gene knockout kit via CRISPR, HDR mediated
  $1,657.00
4 Weeks*

Frequently Bought Together (3)

MR227304 Esr1 (Myc-DDK-tagged) - Mouse estrogen receptor 1 (alpha) (Esr1)
10 ug
$836.00
GE100003 pCAS-Scramble, pCas-Guide vector with a scrambled sequence as a negative control (10 µg)
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$470.00
TT300007S A non-viral, non-electroporation, non-liposomal transfection kit using engineered mammalian proteins, tailored for high-efficiency delivery into a wide range of primary cells and difficult to transfect cell lines such as immune cells, stem cells, and neuronal cells.
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Other products for "Esr1 or NM_001302531"

Specifications
Specifications
Product Data
Format 2 gRNA vectors, 1 Luciferase-Puro donor, 1 scramble control
Vector Luciferase-Puro
Target Symbol Esr1
Locus ID 13982
Components

KN305380G1, Esr1 gRNA vector 1 in pCas-Guide CRISPR vector

KN305380G2, Esr1 gRNA vector 2 in pCas-Guide CRISPR vector

KN305380LPD, donor DNA containing left and right homologous arms and Luciferase-Puro functional cassette.

GE100003, scramble sequence in pCas-Guide vector
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq NM_001302531, NM_001302532, NM_001302533, NM_007956, NR_126357
UniProt ID P19785
Synonyms ER; ER-alpha; ERa; ERalpha; ESR; Estr; Estra; Nr3a1
Summary This gene encodes an estrogen receptor, a member of the nuclear hormone family of intracellular receptors. The encoded protein, activated by the sex hormone estrogen, is a transcription factor composed of several domains important for hormone binding, DNA binding, and activation of transcription. Estrogen and its receptors are essential for sexual development and reproductive function, but also play a role in other tissues such as bone. Similar genes in human have been implicated in pathological processes including breast cancer, endometrial cancer, and osteoporosis. Alternative splicing results in multiple transcript variants. provided by RefSeq, Oct 2014
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Other Versions
SKU Description Size Price
GA201299 Esr1 CRISPRa kit - CRISPR gene activation of mouse estrogen receptor 1 (alpha) 1 kit
$1,657.00
KN305380 Esr1 - mouse gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN305380BN Esr1 - mouse gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN305380RB Esr1 - mouse gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN505380 Esr1 - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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