Eef2k Mouse Gene Knockout Kit (CRISPR)

CAT#: KN305017RB

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Eef2k - mouse gene knockout kit via CRISPR, HDR mediated



HDR-mediated knockout kit validation


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USD 1,290.00


Availability*
4 Weeks

Size
    • 1 kit

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Specifications

Product Data
Format 2 gRNA vectors, 1 RFP-BSD donor, 1 scramble control
Donor DNA RFP-BSD
Symbol Eef2k
Locus ID 13631
Kit Components

KN305017G1, Eef2k gRNA vector 1 in pCas-Guide CRISPR vector

KN305017G2, Eef2k gRNA vector 2 in pCas-Guide CRISPR vector

KN305017RB-D, donor DNA containing left and right homologous arms and RFP-BSD functional cassette.

GE100003, scramble sequence in pCas-Guide vector

Disclaimer The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq NM_001251826, NM_001267710, NM_001267711, NM_007908
Synonyms C86191; eEF-2K
Summary Threonine kinase that regulates protein synthesis by controlling the rate of peptide chain elongation. Upon activation by a variety of upstream kinases including AMPK or TRPM7, phosphorylates the elongation factor EEF2 at a single site, renders it unable to bind ribosomes and thus inactive. In turn, the rate of protein synthesis is reduced.[UniProtKB/Swiss-Prot Function]

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
68 Mouse Clones
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