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Dgat2 Mouse Gene Knockout Kit (CRISPR)

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SKU
KN304521
Dgat2 - mouse gene knockout kit via CRISPR, HDR mediated
  $1,657.00
4 Weeks*

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Other products for "Dgat2 or BC043447"

Specifications
Specifications
Product Data
Format 2 gRNA vectors, 1 GFP-puro donor, 1 scramble control
Vector GFP-puro
Target Symbol Dgat2
Locus ID 67800
Components

KN304521G1, Dgat2 gRNA vector 1 in pCas-Guide CRISPR vector

KN304521G2, Dgat2 gRNA vector 2 in pCas-Guide CRISPR vector

KN304521D, donor DNA containing left and right homologous arms and GFP-puro functional cassette.

GE100003, scramble sequence in pCas-Guide vector
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq NM_026384
UniProt ID Q9DCV3
Synonyms 0610010B06Rik; ARAT; DGAT-2
Summary Essential acyltransferase that catalyzes the terminal and only committed step in triacylglycerol synthesis by using diacylglycerol and fatty acyl CoA as substrates. Required for synthesis and storage of intracellular triglycerides. Probably plays a central role in cytosolic lipid accumulation. In liver, is primarily responsible for incorporating endogenously synthesized fatty acids into triglycerides. Functions also as an acyl-CoA retinol acyltransferase (ARAT) (By similarity).UniProtKB/Swiss-Prot Function
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Other Versions
SKU Description Size Price
KN304521BN Dgat2 - mouse gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN304521LP Dgat2 - mouse gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN304521RB Dgat2 - mouse gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN504521 Dgat2 - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

file-alt Citations

Mouse lipogenic proteins promote the co-accumulation of triacylglycerols and sesquiterpenes in plant cells
Cai, Whitehead, Chappell et al
Planta (2019)
AI Summary: In this study, the pCMV6-MmDGAT2 construct from OriGene was used as the source of the mouse DGAT2 gene, enabling the co-expression experiments that demonstrated enhanced lipid droplet formation and sesquiterpene accumulation in plant cells.
Snippet: 2016) using primers FDPSF and FDPSR. The mouse DGAT2 (GenBank accession no. BC043447) open reading frame was subcloned from pCMV6-MmDGAT2 construct (purchased from OriGene Global, Rockville, MD, USA) using primers DGAT2F and DGAT2R
Showing 1-1 of 1 papers.
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