Cxcr3 Mouse Gene Knockout Kit (CRISPR)

CAT#: KN304051RB

Cxcr3 - mouse gene knockout kit via CRISPR, HDR mediated

Product Images

Specifications

Product Data

• Format: 2 gRNA vectors, 1 RFP-BSD donor, 1 scramble control
• Donor DNA: RFP-BSD
• Symbol: Cxcr3
• Locus ID: 12766
• Components:

  KN304051G1, Cxcr3 gRNA vector 1 in pCas-Guide CRISPR vector

  KN304051G2, Cxcr3 gRNA vector 2 in pCas-Guide CRISPR vector

  KN304051RBD, donor DNA containing left and right homologous arms and RFP-BSD functional cassette.

  GE100003, scramble sequence in pCas-Guide vector

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.

Reference Data

• RefSeq: NM_009910
• UniProt ID: O88410
• Synonyms: Cd183; Cmkar3
• Summary: This gene encodes a transmembrane protein that functions as a receptor for C-X-R chemokines. Signalling through this protein regulates a variety of biological processes, including inflammation, immunity, and would healing. This protein also plays a role in tumor growth and metastasis. [provided by RefSeq, May 2015]