Chd7 Mouse Gene Knockout Kit (CRISPR)

CAT#: KN303251RB

Chd7 - mouse gene knockout kit via CRISPR, HDR mediated

Product Images

Specifications

Product Data

• Format: 2 gRNA vectors, 1 RFP-BSD donor, 1 scramble control
• Donor DNA: RFP-BSD
• Symbol: Chd7
• Locus ID: 320790
• Components:

  KN303251G1, Chd7 gRNA vector 1 in pCas-Guide CRISPR vector

  KN303251G2, Chd7 gRNA vector 2 in pCas-Guide CRISPR vector

  KN303251RBD, donor DNA containing left and right homologous arms and RFP-BSD functional cassette.

  GE100003, scramble sequence in pCas-Guide vector

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.

Reference Data

• RefSeq: NM_001081417, NM_001277149, NM_001033395
• UniProt ID: A2AJK6
• Synonyms: A730019I05Rik; Cycn; Cyn; Dz; Edy; Flo; Lda; Mt; Obt; RP23-464N23.1; Todo; WBE1; Whi
• Summary: This gene encodes a protein containing two chromodomains and an ATP-binding helicase domain that functions as a regulator of transcription. Mutations in this gene result in an array of development defects, including inner ear problems. Mice defective for this gene exhibit many of the clinical features of the CHARGE syndrome caused by mutations in the homologous gene in human. [provided by RefSeq, Sep 2015]