Atp6v0a2 Mouse Gene Knockout Kit (CRISPR)

CAT#: KN301808RB

Atp6v0a2 - mouse gene knockout kit via CRISPR, HDR mediated

Product Images

Specifications

Product Data

• Format: 2 gRNA vectors, 1 RFP-BSD donor, 1 scramble control
• Donor DNA: RFP-BSD
• Symbol: Atp6v0a2
• Locus ID: 21871
• Components:

  KN301808G1, Atp6v0a2 gRNA vector 1 in pCas-Guide CRISPR vector

  KN301808G2, Atp6v0a2 gRNA vector 2 in pCas-Guide CRISPR vector

  KN301808RBD, donor DNA containing left and right homologous arms and RFP-BSD functional cassette.

  GE100003, scramble sequence in pCas-Guide vector

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.

Reference Data

• RefSeq: NM_011596
• UniProt ID: P15920
• Synonyms: 8430408C20Rik; AI385560; ATP6a2; Atp6n1d; Atp6n2; AW489264; C76904; ISF; J6B7; SHIF; Stv1; Tj6
• Summary: This gene encodes a subunit of vacuolar ATPase, a multimeric enzyme that localizes to intracellular vesicles and to the plasma membrane of specialized cells. The encoded protein is a component of the V(0) domain, which functions in proton translocation across membranes. Function of this gene is important in fetal-specific immune suppression during pregnancy. [provided by RefSeq, May 2013]