Atg7 Mouse Gene Knockout Kit (CRISPR)

SKU
KN301741RB
Atg7 - mouse gene knockout kit via CRISPR, HDR mediated
  $1,657.00
4 Weeks*
Specifications
Specifications
Product Data
Format 2 gRNA vectors, 1 RFP-BSD donor, 1 scramble control
Vector RFP-BSD
Target Symbol Atg7
Locus ID 74244
Components

KN301741G1, Atg7 gRNA vector 1 in pCas-Guide CRISPR vector

KN301741G2, Atg7 gRNA vector 2 in pCas-Guide CRISPR vector

KN301741RBD, donor DNA containing left and right homologous arms and RFP-BSD functional cassette.

GE100003, scramble sequence in pCas-Guide vector

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq NM_001253717, NM_001253718, NM_028835
UniProt ID Q9D906
Synonyms 1810013K23Rik; Agp7; Apg7l; Atg7l; Gm21553
Summary This gene encodes an E1-like activating enzyme that is essential for autophagy and cytoplasmic to vacuole transport. The encoded protein is also thought to modulate p53-dependent cell cycle pathways during prolonged metabolic stress. It has been associated with multiple functions, including axon membrane trafficking, axonal homeostasis, mitophagy, adipose differentiation, and hematopoietic stem cell maintenance. Alternative splicing results in multiple transcript variants. provided by RefSeq, Sep 2015
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Other Versions
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GA209799 Atg7 CRISPRa kit - CRISPR gene activation of mouse autophagy related 7 1 kit
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KN301741 Atg7 - mouse gene knockout kit via CRISPR, HDR mediated 1 kit
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KN301741BN Atg7 - mouse gene knockout kit via CRISPR, HDR mediated 1 kit
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$1,657.00
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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