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Atg5 Mouse Gene Knockout Kit (CRISPR)

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SKU
KN301740LP
Atg5 - mouse gene knockout kit via CRISPR, HDR mediated
  $1,657.00
4 Weeks*

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Specifications
Specifications
Product Data
Format 2 gRNA vectors, 1 Luciferase-Puro donor, 1 scramble control
Vector Luciferase-Puro
Target Symbol Atg5
Locus ID 11793
Components

KN301740G1, Atg5 gRNA vector 1 in pCas-Guide CRISPR vector

KN301740G2, Atg5 gRNA vector 2 in pCas-Guide CRISPR vector

KN301740LPD, donor DNA containing left and right homologous arms and Luciferase-Puro functional cassette.

GE100003, scramble sequence in pCas-Guide vector
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq NM_053069
UniProt ID Q99J83
Synonyms 2010107M05Rik; 3110067M24Rik; Apg5l; Atg5l; AW319544; C88337; Paddy
Summary The protein encoded by this gene, in combination with autophagy protein 12, functions as an E1-like activating enzyme in a ubiquitin-like conjugating system. The encoded protein is involved in several cellular processes, including autophagic vesicle formation, mitochondrial quality control after oxidative damage, negative regulation of the innate antiviral immune response, lymphocyte development and proliferation, MHC II antigen presentation, adipocyte differentiation, and apoptosis. Two transcript variants encoding different protein isoforms have been found for this gene. provided by RefSeq, Sep 2015
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Documents
Resources
Other Versions
SKU Description Size Price
GA200227 Atg5 CRISPRa kit - CRISPR gene activation of mouse autophagy related 5 1 kit
$1,657.00
KN301740 Atg5 - mouse gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN301740BN Atg5 - mouse gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN301740RB Atg5 - mouse gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN501740 Atg5 - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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