Adrb2 Mouse Gene Knockout Kit (CRISPR)

SKU
KN300934LP
Adrb2 - mouse gene knockout kit via CRISPR, HDR mediated
  $1,657.00
4 Weeks*
Specifications
Specifications
Product Data
Format 2 gRNA vectors, 1 Luciferase-Puro donor, 1 scramble control
Vector Luciferase-Puro
Target Symbol Adrb2
Locus ID 11555
Components

KN300934G1, Adrb2 gRNA vector 1 in pCas-Guide CRISPR vector

KN300934G2, Adrb2 gRNA vector 2 in pCas-Guide CRISPR vector

KN300934LPD, donor DNA containing left and right homologous arms and Luciferase-Puro functional cassette.

GE100003, scramble sequence in pCas-Guide vector

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq NM_007420
UniProt ID P18762
Synonyms Adrb-2; Badm; Gpcr7
Summary This intronless gene belongs to the G-protein-coupled receptor superfamily, which includes transmembrane proteins that play a role in signal transduction across biological membranes resulting in a variety of physiological responses. The encoded protein is a beta-2 adrenergic receptor which is activated by catecholamine ligands such as adrenaline and epinephrine. The protein participates in the classical signaling pathway involving G protein, adenylyl cyclase, cAMP (3'-5'-cyclic adenosine monophosphate) and protein kinase A (PKA). In humans, this gene is implicated in susceptibility to nocturnal asthma, obesity and type 2 diabetes. provided by RefSeq, Apr 2013
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Other Versions
SKU Description Size Price
GA200105 Adrb2 CRISPRa kit - CRISPR gene activation of mouse adrenergic receptor, beta 2 1 kit
$1,657.00
KN300934 Adrb2 - mouse gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN300934BN Adrb2 - mouse gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN300934RB Adrb2 - mouse gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN500934 Adrb2 - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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