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WRN Human Gene Knockout Kit (CRISPR)

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SKU
KN222919LP
WRN - human gene knockout kit via CRISPR, HDR mediated
  $1,657.00
4 Weeks*

Frequently Bought Together (4)

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Other products for "WRN or NM_000553"

Specifications
Specifications
Product Data
Format 2 gRNA vectors, 1 Luciferase-Puro donor, 1 scramble control
Vector Luciferase-Puro
Target Symbol WRN
Locus ID 7486
Components

KN222919G1, WRN gRNA vector 1 in pCas-Guide CRISPR vector

KN222919G2, WRN gRNA vector 2 in pCas-Guide CRISPR vector

KN222919LPD, donor DNA containing left and right homologous arms and Luciferase-Puro functional cassette.

GE100003, scramble sequence in pCas-Guide vector
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq NM_000553
UniProt ID Q14191
Synonyms RECQ3; RECQL2; RECQL3
Summary This gene encodes a member of the RecQ subfamily of DNA helicase proteins. The encoded nuclear protein is important in the maintenance of genome stability and plays a role in DNA repair, replication, transcription and telomere maintenance. This protein contains a N-terminal 3' to 5' exonuclease domain, an ATP-dependent helicase domain and RQC (RecQ helicase conserved region) domain in its central region, and a C-terminal HRDC (helicase RNase D C-terminal) domain and nuclear localization signal. Defects in this gene are the cause of Werner syndrome, an autosomal recessive disorder characterized by accelerated aging and an elevated risk for certain cancers. provided by RefSeq, Aug 2017
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Documents
Resources
Other Versions
SKU Description Size Price
GA105162 WRN CRISPRa kit - CRISPR gene activation of human WRN RecQ like helicase 1 kit
$1,657.00
KN222919 WRN - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN222919BN WRN - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN222919RB WRN - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN422919 WRN - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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