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Human WRN activation kit by CRISPRa

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SKU
GA105162
WRN CRISPRa kit - CRISPR gene activation of human WRN RecQ like helicase
  $1,657.00
4 Weeks*

Frequently Bought Together (2)

TA367798 WRN rabbit polyclonal antibody
100 ul
$310.00
RC222919 WRN (Myc-DDK-tagged)-Human Werner syndrome, RecQ helicase-like (WRN)
10 ug
$1,837.00

Other products for "WRN"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol WRN
Locus ID 7486
Components

GA105162G1, WRN gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA105162G2, WRN gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA105162G3, WRN gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_000553
UniProt ID Q14191
Synonyms RECQ3; RECQL2; RECQL3
Summary This gene encodes a member of the RecQ subfamily of DNA helicase proteins. The encoded nuclear protein is important in the maintenance of genome stability and plays a role in DNA repair, replication, transcription and telomere maintenance. This protein contains a N-terminal 3' to 5' exonuclease domain, an ATP-dependent helicase domain and RQC (RecQ helicase conserved region) domain in its central region, and a C-terminal HRDC (helicase RNase D C-terminal) domain and nuclear localization signal. Defects in this gene are the cause of Werner syndrome, an autosomal recessive disorder characterized by accelerated aging and an elevated risk for certain cancers. provided by RefSeq, Aug 2017
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Documents
Resources
Other Versions
SKU Description Size Price
KN222919 WRN - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN222919BN WRN - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN222919LP WRN - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN222919RB WRN - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN422919 WRN - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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