ADCY5 Human Gene Knockout Kit (CRISPR)
CAT#: KN222906BN
ADCY5 - human gene knockout kit via CRISPR, HDR mediated
Functional Cassette: GFP-puro Luciferase-Puro RFP-BSD
HDR-mediated knockout kit validation
USD 1,657.00
4 Weeks*
Specifications
Product Data | |
Format | 2 gRNA vectors, 1 mBFP-Neo donor, 1 scramble control |
Donor DNA | mBFP-Neo |
Symbol | ADCY5 |
Locus ID | 111 |
Components |
KN222906G1, ADCY5 gRNA vector 1 in pCas-Guide CRISPR vector KN222906G2, ADCY5 gRNA vector 2 in pCas-Guide CRISPR vector KN222906BND, donor DNA containing left and right homologous arms and mBFP-Neo functional cassette. GE100003, scramble sequence in pCas-Guide vector |
Disclaimer | These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process. |
Reference Data | |
RefSeq | NM_001199642, NM_183357 |
UniProt ID | O95622 |
Synonyms | AC5; FDFM |
Summary | This gene encodes a member of the membrane-bound adenylyl cyclase enzymes. Adenylyl cyclases mediate G protein-coupled receptor signaling through the synthesis of the second messenger cAMP. Activity of the encoded protein is stimulated by the Gs alpha subunit of G protein-coupled receptors and is inhibited by protein kinase A, calcium and Gi alpha subunits. Single nucleotide polymorphisms in this gene may be associated with low birth weight and type 2 diabetes. Alternatively spliced transcript variants that encode different isoforms have been observed for this gene. [provided by RefSeq, Dec 2010] |
Documents
Product Manuals |
FAQs |
SDS |
Resources
Other Versions
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KN222906 | ADCY5 - human gene knockout kit via CRISPR, HDR mediated |
USD 1,657.00 |
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KN222906LP | ADCY5 - human gene knockout kit via CRISPR, HDR mediated |
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KN222906RB | ADCY5 - human gene knockout kit via CRISPR, HDR mediated |
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KN422906 | ADCY5 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. |
USD 1,657.00 |
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GA100073 | ADCY5 CRISPRa kit - CRISPR gene activation of human adenylate cyclase 5 |
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