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XYLT1 Human Gene Knockout Kit (CRISPR)

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SKU
KN222133RB
XYLT1 - human gene knockout kit via CRISPR, HDR mediated
  $1,657.00
4 Weeks*

Frequently Bought Together (3)

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Other products for "XYLT1 or NM_022166"

Specifications
Specifications
Product Data
Format 2 gRNA vectors, 1 RFP-BSD donor, 1 scramble control
Vector RFP-BSD
Target Symbol XYLT1
Locus ID 64131
Components

KN222133G1, XYLT1 gRNA vector 1 in pCas-Guide CRISPR vector, Target Sequence: AATTTCAGCAGCCTCGACTC

KN222133G2, XYLT1 gRNA vector 2 in pCas-Guide CRISPR vector, Target Sequence: TGCTGCAGACGCTGGTCGTG

KN222133RBD, donor DNA containing left and right homologous arms and RFP-BSD functional cassette.

Homologous arm and RFP-BSD sequences:

pUC vector backbone in gray; Left arm sequence in blue; RFP-BSD in green; Right arm in violet

ATGAAGGGAT CAGACTGTGG CTCTGACACT CCTGAAATGT TTCTCACGTG TCCACCTGCC AACCGGTCTG GTACCGACAG AAGATCCCTG GACCGCGAAC TCCGGGGCTA GGAGCTTCCT CCACGCACTG CCTCCTTCCA GCGGCCCACA GGGAAAACAG GACCTCGGGA CCCCCTCTCT TCCTGACCTC CCCTGGATTC TGAGCGGGCC CACCCTCAAC CAAAGGTCCC CTGTTTCGCG GCCCCTGCCT CTCTTTTTCC GCCTTGGGAA TTGTCCCCCT CGCCCCCCAT CCTACTCCCA CTACGTCCTG AGGGGTGTCT GTCTTCTCTG ATCGCCCCCA CCCCCTTCCT TTCCCTCCTC CTTTTCCTCC CTCGGCTCCT CCCCCAGGCC CCGCCCTCTC CGCCTCGGCC CGCGTCCCCC CGGCGCCTTC CCCATCACCC TCCCCTCCAG CGGGGACAGG GGTGTGGGGA GGGGGGCGGC GGCGGCGGCC CGAGCGGGAG CCCGAGCGGC AGCCGGCGGC CGCGGGAGCT GCGGGGAGCG CGGGGGCGGC CCGGAGCGTG CCGGGGTCCC CGCGCCTCGC TCGCCGGCCG CGCTCCGAAG TCTGGTAAGA TGCCCTTTCG GCTCGCGCCC CGCGGCGAGG GAGGGAGGAA GGCAGCCCGA CCCCACGCCC CCCTAGCCCT TGAACTCGGT CATCAGACTG GGACTCTGCA AGCCTACCGA CTCCACATCG CCTCTTGCCC CGGGAAGCCG GGTGGGGTCC CTGCCAAGGC TCAGGGGTCG TGGGCTGCCC CTTTCAGAGT CTGAGCACGG ACCCCTTGGG GTCTGGGGGA AGTTTTCTCC AGCGGGGGCG CTTTGGGGGT TACCGGAGCC TGGCTGGGTT CCTGTTCCCC ATCACTCTTG CTGGGGACCC CAGGTGACTT GCTCCGTGCG TGTAGGTCTT GGTGACTCGC TCCCTGCCTG AGTGAGTGGA TCTCCCCGGA TCCTCAGCCG CTGTTCCTGG GCGGTTGTCG CAGCAGCATC TCTCTGGTTT TTGCCGAGCT GGGTGCAGAC AGTTGAGCCC TCTGTTCGTC CTGGCCTGCG ATGAGGGCTG AGCTGGGCGT CCCAAGTCCC CGACCATGCC CCTGAATCAA TACTCAGTCC GGGGTGTCTG GTCTTACTTT GGGTCTTCTG TTTCTCTTCT CTGGATGTTT GAGCCTTCCG

GE100003, scramble sequence in pCas-Guide vector
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq NM_022166
UniProt ID Q86Y38
Synonyms DBQD2; PXYLT1; XT-I; XT1; XTI; xylT-I; XYLTI
Summary This locus encodes a xylosyltransferase enzyme. The encoded protein catalyzes transfer of UDP-xylose to serine residues of an acceptor protein substrate. This transfer reaction is necessary for biosynthesis of glycosaminoglycan chains. Mutations in this gene have been associated with increased severity of pseudoxanthoma elasticum.provided by RefSeq, Nov 2009
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Documents
Resources
Other Versions
SKU Description Size Price
GA111993 XYLT1 CRISPRa kit - CRISPR gene activation of human xylosyltransferase 1 1 kit
$1,657.00
KN222133 XYLT1 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN222133BN XYLT1 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN222133LP XYLT1 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN422133 XYLT1 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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