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ABCA1 Human Gene Knockout Kit (CRISPR)

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SKU
KN221861LP
ABCA1 - human gene knockout kit via CRISPR, HDR mediated
  $1,657.00
4 Weeks*

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Other products for "ABCA1 or BC034824"

Specifications
Specifications
Product Data
Format 2 gRNA vectors, 1 Luciferase-Puro donor, 1 scramble control
Vector Luciferase-Puro
Target Symbol ABCA1
Locus ID 19
Components

KN221861G1, ABCA1 gRNA vector 1 in pCas-Guide CRISPR vector

KN221861G2, ABCA1 gRNA vector 2 in pCas-Guide CRISPR vector

KN221861LPD, donor DNA containing left and right homologous arms and Luciferase-Puro functional cassette.

GE100003, scramble sequence in pCas-Guide vector
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq NM_005502
UniProt ID O95477
Synonyms ABC-1; ABC1; CERP; HDLDT1; TGD
Summary The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ABC1 subfamily. Members of the ABC1 subfamily comprise the only major ABC subfamily found exclusively in multicellular eukaryotes. With cholesterol as its substrate, this protein functions as a cholesteral efflux pump in the cellular lipid removal pathway. Mutations in both alleles of this gene cause Tangier disease and familial high-density lipoprotein (HDL) deficiency. provided by RefSeq, Sep 2019
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Documents
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Other Versions
SKU Description Size Price
GA100011 ABCA1 CRISPRa kit - CRISPR gene activation of human ATP binding cassette subfamily A member 1 1 kit
$1,657.00
KN221861 ABCA1 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN221861BN ABCA1 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN221861RB ABCA1 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN421861 ABCA1 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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