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XRN1 Human Gene Knockout Kit (CRISPR)

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SKU
KN221062BN
XRN1 - human gene knockout kit via CRISPR, HDR mediated
  $1,657.00
4 Weeks*

Frequently Bought Together (3)

RC221062 XRN1 (Myc-DDK-tagged)-Human 5'-3' exoribonuclease 1 (XRN1), transcript variant 1
10 ug
$1,434.00
GE100003 pCAS-Scramble, pCas-Guide vector with a scrambled sequence as a negative control (10 µg)
10 ug
$470.00
TT300007S A non-viral, non-electroporation, non-liposomal transfection kit using engineered mammalian proteins, tailored for high-efficiency delivery into a wide range of primary cells and difficult to transfect cell lines such as immune cells, stem cells, and neuronal cells.
20 ul
$265.00

Other products for "XRN1 or AK096177"

Specifications
Specifications
Product Data
Format 2 gRNA vectors, 1 mBFP-Neo donor, 1 scramble control
Vector mBFP-Neo
Target Symbol XRN1
Locus ID 54464
Components

KN221062G1, XRN1 gRNA vector 1 in pCas-Guide CRISPR vector

KN221062G2, XRN1 gRNA vector 2 in pCas-Guide CRISPR vector

KN221062BND, donor DNA containing left and right homologous arms and mBFP-Neo functional cassette.

GE100003, scramble sequence in pCas-Guide vector
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq NM_001042604, NM_001282857, NM_001282859, NM_019001
UniProt ID Q8IZH2
Synonyms SEP1
Summary This gene encodes a member of the 5'-3' exonuclease family. The encoded protein may be involved in replication-dependent histone mRNA degradation, and interacts directly with the enhancer of mRNA-decapping protein 4. In addition to mRNA metabolism, a similar protein in yeast has been implicated in a variety of nuclear and cytoplasmic functions, including homologous recombination, meiosis, telomere maintenance, and microtubule assembly. Mutations in this gene are associated with osteosarcoma, suggesting that the encoded protein may also play a role in bone formation. Alternative splicing results in multiple transcript variants. provided by RefSeq, Sep 2013
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Other Versions
SKU Description Size Price
GA110115 XRN1 CRISPRa kit - CRISPR gene activation of human 5'-3' exoribonuclease 1 1 kit
$1,657.00
KN221062 XRN1 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN221062LP XRN1 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN221062RB XRN1 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN421062 XRN1 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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