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Phospholipase A2 (PLA2G4A) Human Gene Knockout Kit (CRISPR)

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SKU
KN220972LP
PLA2G4A - human gene knockout kit via CRISPR, HDR mediated
  $1,657.00
4 Weeks*

Frequently Bought Together (3)

RC220972 PLA2G4A (Myc-DDK-tagged)-Human phospholipase A2, group IVA (cytosolic, calcium-dependent) (PLA2G4A)
10 ug
$1,029.00
GE100003 pCAS-Scramble, pCas-Guide vector with a scrambled sequence as a negative control (10 µg)
10 ug
$470.00
TT300007S A non-viral, non-electroporation, non-liposomal transfection kit using engineered mammalian proteins, tailored for high-efficiency delivery into a wide range of primary cells and difficult to transfect cell lines such as immune cells, stem cells, and neuronal cells.
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Other products for "Phospholipase A2 or NM_001311193"

Specifications
Specifications
Product Data
Format 2 gRNA vectors, 1 Luciferase-Puro donor, 1 scramble control
Vector Luciferase-Puro
Target Symbol Phospholipase A2
Locus ID 5321
Components

KN220972G1, Phospholipase A2 gRNA vector 1 in pCas-Guide CRISPR vector

KN220972G2, Phospholipase A2 gRNA vector 2 in pCas-Guide CRISPR vector

KN220972LPD, donor DNA containing left and right homologous arms and Luciferase-Puro functional cassette.

GE100003, scramble sequence in pCas-Guide vector
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq NM_001311193, NM_024420
UniProt ID P47712
Synonyms cPLA2; cPLA2-alpha; PLA2G4
Summary This gene encodes a member of the cytosolic phospholipase A2 group IV family. The enzyme catalyzes the hydrolysis of membrane phospholipids to release arachidonic acid which is subsequently metabolized into eicosanoids. Eicosanoids, including prostaglandins and leukotrienes, are lipid-based cellular hormones that regulate hemodynamics, inflammatory responses, and other intracellular pathways. The hydrolysis reaction also produces lysophospholipids that are converted into platelet-activating factor. The enzyme is activated by increased intracellular Ca(2+) levels and phosphorylation, resulting in its translocation from the cytosol and nucleus to perinuclear membrane vesicles. Alternative splicing results in multiple transcript variants. provided by RefSeq, Jul 2015
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Other Versions
SKU Description Size Price
GA103582 PLA2G4A CRISPRa kit - CRISPR gene activation of human phospholipase A2 group IVA 1 kit
$1,657.00
KN220972 PLA2G4A - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN220972BN PLA2G4A - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN220972RB PLA2G4A - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN420972 PLA2G4A - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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