p73 (TP73) Human Gene Knockout Kit (CRISPR)

SKU
KN220864RB
TP73 - human gene knockout kit via CRISPR, HDR mediated
  $1,657.00
4 Weeks*
Specifications
Specifications
Product Data
Format 2 gRNA vectors, 1 RFP-BSD donor, 1 scramble control
Vector RFP-BSD
Target Symbol p73
Locus ID 7161
Components

KN220864G1, p73 gRNA vector 1 in pCas-Guide CRISPR vector

KN220864G2, p73 gRNA vector 2 in pCas-Guide CRISPR vector

KN220864RBD, donor DNA containing left and right homologous arms and RFP-BSD functional cassette.

GE100003, scramble sequence in pCas-Guide vector

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq NM_001126240, NM_001126241, NM_001126242, NM_001204184, NM_001204185, NM_001204186, NM_001204187, NM_001204188, NM_001204189, NM_001204190, NM_001204191, NM_001204192, NM_005427
UniProt ID O15350
Synonyms P73
Summary This gene encodes a member of the p53 family of transcription factors involved in cellular responses to stress and development. It maps to a region on chromosome 1p36 that is frequently deleted in neuroblastoma and other tumors, and thought to contain multiple tumor suppressor genes. The demonstration that this gene is monoallelically expressed (likely from the maternal allele), supports the notion that it is a candidate gene for neuroblastoma. Many transcript variants resulting from alternative splicing and/or use of alternate promoters have been found for this gene, but the biological validity and the full-length nature of some variants have not been determined. provided by RefSeq, Feb 2011
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Other Versions
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GA104945 TP73 CRISPRa kit - CRISPR gene activation of human tumor protein p73 1 kit
$1,657.00
KN220864 TP73 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN220864BN TP73 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN220864LP TP73 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN420864 TP73 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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