MAP4K1 Human Gene Knockout Kit (CRISPR)

CAT#: KN220698RB

MAP4K1 - human gene knockout kit via CRISPR, HDR mediated

Product Images

Specifications

Product Data

• Format: 2 gRNA vectors, 1 RFP-BSD donor, 1 scramble control
• Donor DNA: RFP-BSD
• Symbol: MAP4K1
• Locus ID: 11184
• Components:

  KN220698G1, MAP4K1 gRNA vector 1 in pCas-Guide CRISPR vector

  KN220698G2, MAP4K1 gRNA vector 2 in pCas-Guide CRISPR vector

  KN220698RBD, donor DNA containing left and right homologous arms and RFP-BSD functional cassette.

  GE100003, scramble sequence in pCas-Guide vector

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.

Reference Data

• RefSeq: NM_001042600, NM_007181
• UniProt ID: Q92918
• Synonyms: HPK1
• Summary: Serine/threonine-protein kinase, which may play a role in the response to environmental stress. Appears to act upstream of the JUN N-terminal pathway. May play a role in hematopoietic lineage decisions and growth regulation. Able to autophosphorylate.[UniProtKB/Swiss-Prot Function]