DGCR8 Human Gene Knockout Kit (CRISPR)
Specifications
| Product Data | |
| Format | 2 gRNA vectors, 1 mBFP-Neo donor, 1 scramble control |
|---|---|
| Vector | mBFP-Neo |
| Target Symbol | DGCR8 |
| Locus ID | 54487 |
| Components |
KN219451G1, DGCR8 gRNA vector 1 in pCas-Guide CRISPR vector KN219451G2, DGCR8 gRNA vector 2 in pCas-Guide CRISPR vector KN219451BND, donor DNA containing left and right homologous arms and mBFP-Neo functional cassette. GE100003, scramble sequence in pCas-Guide vector |
| OTI Disclaimer | These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process. |
| Reference Data | |
| RefSeq | NM_001190326, NM_022720 |
| UniProt ID | Q8WYQ5 |
| Synonyms | C22orf12; DGCRK6; Gy1; pasha |
| Summary | This gene encodes a subunit of the microprocessor complex which mediates the biogenesis of microRNAs from the primary microRNA transcript. The encoded protein is a double-stranded RNA binding protein that functions as the non-catalytic subunit of the microprocessor complex. This protein is required for binding the double-stranded RNA substrate and facilitates cleavage of the RNA by the ribonuclease III protein, Drosha. Alternate splicing results in multiple transcript variants. provided by RefSeq, Jun 2010 |
| Shipping | Ambient |
Reviews
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| GA110131 | DGCR8 CRISPRa kit - CRISPR gene activation of human DGCR8 microprocessor complex subunit | 1 kit |
$1,657.00
|
|
| KN219451 | DGCR8 - human gene knockout kit via CRISPR, HDR mediated | 1 kit |
$1,657.00
|
|
| KN219451LP | DGCR8 - human gene knockout kit via CRISPR, HDR mediated | 1 kit |
$1,657.00
|
|
| KN219451RB | DGCR8 - human gene knockout kit via CRISPR, HDR mediated | 1 kit |
$1,657.00
|
|
| KN419451 | DGCR8 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. | 1 kit |
$1,657.00
|
|
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