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LCK Human Gene Knockout Kit (CRISPR)

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SKU
KN219375RB
LCK - human gene knockout kit via CRISPR, HDR mediated
  $1,657.00
4 Weeks*

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Other products for "LCK or NM_001042771"

Specifications
Specifications
Product Data
Format 2 gRNA vectors, 1 RFP-BSD donor, 1 scramble control
Vector RFP-BSD
Target Symbol LCK
Locus ID 3932
Components

KN219375G1, LCK gRNA vector 1 in pCas-Guide CRISPR vector

KN219375G2, LCK gRNA vector 2 in pCas-Guide CRISPR vector

KN219375RBD, donor DNA containing left and right homologous arms and RFP-BSD functional cassette.

GE100003, scramble sequence in pCas-Guide vector
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq NM_001042771, NM_001330468, NM_005356
UniProt ID P06239
Synonyms IMD22; LSK; p56lck; pp58lck; YT16
Summary This gene is a member of the Src family of protein tyrosine kinases (PTKs). The encoded protein is a key signaling molecule in the selection and maturation of developing T-cells. It contains N-terminal sites for myristylation and palmitylation, a PTK domain, and SH2 and SH3 domains which are involved in mediating protein-protein interactions with phosphotyrosine-containing and proline-rich motifs, respectively. The protein localizes to the plasma membrane and pericentrosomal vesicles, and binds to cell surface receptors, including CD4 and CD8, and other signaling molecules. Multiple alternatively spliced variants encoding different isoforms have been described. provided by RefSeq, Aug 2016
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Documents
Resources
Other Versions
SKU Description Size Price
GA102666 LCK CRISPRa kit - CRISPR gene activation of human LCK proto-oncogene, Src family tyrosine kinase 1 kit
$1,657.00
KN219375 LCK - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN219375BN LCK - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN219375LP LCK - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN419375 LCK - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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