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Human LCK activation kit by CRISPRa

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SKU
GA102666
LCK CRISPRa kit - CRISPR gene activation of human LCK proto-oncogene, Src family tyrosine kinase
  $1,657.00
4 Weeks*

Frequently Bought Together (2)

TA324976 LCK Antibody (N-term)
400 ul
$645.00
RC219430 LCK (Myc-DDK-tagged)-Human lymphocyte-specific protein tyrosine kinase (LCK), transcript variant 1
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Other products for "LCK"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol LCK
Locus ID 3932
Components

GA102666G1, LCK gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA102666G2, LCK gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA102666G3, LCK gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_001042771, NM_001330468, NM_005356
UniProt ID P06239
Synonyms IMD22; LSK; p56lck; pp58lck; YT16
Summary This gene is a member of the Src family of protein tyrosine kinases (PTKs). The encoded protein is a key signaling molecule in the selection and maturation of developing T-cells. It contains N-terminal sites for myristylation and palmitylation, a PTK domain, and SH2 and SH3 domains which are involved in mediating protein-protein interactions with phosphotyrosine-containing and proline-rich motifs, respectively. The protein localizes to the plasma membrane and pericentrosomal vesicles, and binds to cell surface receptors, including CD4 and CD8, and other signaling molecules. Multiple alternatively spliced variants encoding different isoforms have been described. provided by RefSeq, Aug 2016
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Documents
Resources
Other Versions
SKU Description Size Price
KN219375 LCK - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN219375BN LCK - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN219375LP LCK - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN219375RB LCK - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN419375 LCK - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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