Desmoplakin (DSP) Human Gene Knockout Kit (CRISPR)
Specifications
| Product Data | |
| Format | 2 gRNA vectors, 1 mBFP-Neo donor, 1 scramble control |
|---|---|
| Vector | mBFP-Neo |
| Target Symbol | Desmoplakin |
| Locus ID | 1832 |
| Components |
KN218822G1, Desmoplakin gRNA vector 1 in pCas-Guide CRISPR vector KN218822G2, Desmoplakin gRNA vector 2 in pCas-Guide CRISPR vector KN218822BND, donor DNA containing left and right homologous arms and mBFP-Neo functional cassette. GE100003, scramble sequence in pCas-Guide vector |
| OTI Disclaimer | These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process. |
| Reference Data | |
| RefSeq | NM_001008844, NM_001319034, NM_004415 |
| UniProt ID | P15924 |
| Synonyms | DCWHKTA; DP; DPI; DPII |
| Summary | This gene encodes a protein that anchors intermediate filaments to desmosomal plaques and forms an obligate component of functional desmosomes. Mutations in this gene are the cause of several cardiomyopathies and keratodermas, including skin fragility-woolly hair syndrome. Alternative splicing results in multiple transcript variants. provided by RefSeq, Jan 2016 |
| Shipping | Ambient |
Reviews
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| GA101283 | DSP CRISPRa kit - CRISPR gene activation of human desmoplakin | 1 kit |
$1,657.00
|
|
| KN218822 | DSP - human gene knockout kit via CRISPR, HDR mediated | 1 kit |
$1,657.00
|
|
| KN218822LP | DSP - human gene knockout kit via CRISPR, HDR mediated | 1 kit |
$1,657.00
|
|
| KN218822RB | DSP - human gene knockout kit via CRISPR, HDR mediated | 1 kit |
$1,657.00
|
|
| KN418822 | DSP - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. | 1 kit |
$1,657.00
|
|
Citations
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