Von Willebrand Factor (VWF) Human Gene Knockout Kit (CRISPR)

SKU
KN218497RB
VWF - human gene knockout kit via CRISPR, HDR mediated
  $1,657.00
4 Weeks*
Specifications
Specifications
Product Data
Format 2 gRNA vectors, 1 RFP-BSD donor, 1 scramble control
Vector RFP-BSD
Target Symbol Von Willebrand Factor
Locus ID 7450
Components

KN218497G1, Von Willebrand Factor gRNA vector 1 in pCas-Guide CRISPR vector

KN218497G2, Von Willebrand Factor gRNA vector 2 in pCas-Guide CRISPR vector

KN218497RBD, donor DNA containing left and right homologous arms and RFP-BSD functional cassette.

GE100003, scramble sequence in pCas-Guide vector

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq NM_000552
UniProt ID P04275
Synonyms F8VWF; VWD
Summary This gene encodes a glycoprotein involved in hemostasis. The encoded preproprotein is proteolytically processed following assembly into large multimeric complexes. These complexes function in the adhesion of platelets to sites of vascular injury and the transport of various proteins in the blood. Mutations in this gene result in von Willebrand disease, an inherited bleeding disorder. An unprocessed pseudogene has been found on chromosome 22. provided by RefSeq, Oct 2015
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Other Versions
SKU Description Size Price
GA105134 VWF CRISPRa kit - CRISPR gene activation of human von Willebrand factor 1 kit
$1,657.00
KN218497 VWF - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN218497BN VWF - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN218497LP VWF - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN418497 VWF - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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