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SIRT1 Human Gene Knockout Kit (CRISPR)

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SKU
KN218134BN
SIRT1 - human gene knockout kit via CRISPR, HDR mediated
  $1,657.00
4 Weeks*

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Other products for "SIRT1 or NM_001142498"

Specifications
Specifications
Product Data
Format 2 gRNA vectors, 1 mBFP-Neo donor, 1 scramble control
Vector mBFP-Neo
Target Symbol SIRT1
Locus ID 23411
Components

KN218134G1, SIRT1 gRNA vector 1 in pCas-Guide CRISPR vector

KN218134G2, SIRT1 gRNA vector 2 in pCas-Guide CRISPR vector

KN218134BND, donor DNA containing left and right homologous arms and mBFP-Neo functional cassette.

GE100003, scramble sequence in pCas-Guide vector
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq NM_001142498, NM_001314049, NM_012238
UniProt ID Q96EB6
Synonyms SIR2; SIR2alpha; SIR2L1
Summary This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class I of the sirtuin family. Alternative splicing results in multiple transcript variants. provided by RefSeq, Dec 2008
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Documents
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Other Versions
SKU Description Size Price
GA108289 SIRT1 CRISPRa kit - CRISPR gene activation of human sirtuin 1 1 kit
$1,657.00
KN218134 SIRT1 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN218134LP SIRT1 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN218134RB SIRT1 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN418134 SIRT1 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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