TRPM7 Human Gene Knockout Kit (CRISPR)

SKU
KN218043BN
TRPM7 - human gene knockout kit via CRISPR, HDR mediated
  $1,657.00
4 Weeks*
Specifications
Specifications
Product Data
Format 2 gRNA vectors, 1 mBFP-Neo donor, 1 scramble control
Vector mBFP-Neo
Target Symbol TRPM7
Locus ID 54822
Components

KN218043G1, TRPM7 gRNA vector 1 in pCas-Guide CRISPR vector

KN218043G2, TRPM7 gRNA vector 2 in pCas-Guide CRISPR vector

KN218043BND, donor DNA containing left and right homologous arms and mBFP-Neo functional cassette.

GE100003, scramble sequence in pCas-Guide vector

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq NM_001301212, NM_017672, NR_149152, NR_149153, NR_149154
UniProt ID Q96QT4
Synonyms ALSPDC; CHAK; CHAK1; LTrpC-7; LTRPC7; TRP-PLIK
Summary This gene belongs to the melastatin subfamily of transient receptor potential family of ion channels. The protein encoded by this gene is both an ion channel and a serine/threonine protein kinase. The kinase activity is essential for the ion channel function, which serves to increase intracellular calcium levels and to help regulate magnesium ion homeostasis. The encoded protein is involved in cytoskeletal organization, cell adhesion, cell migration and organogenesis. Defects in this gene are a cause of amyotrophic lateral sclerosis-parkinsonism/dementia complex of Guam. The gene may also be associated with defects of cardiac function. provided by RefSeq, Aug 2017
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Other Versions
SKU Description Size Price
GA110287 TRPM7 CRISPRa kit - CRISPR gene activation of human transient receptor potential cation channel subfamily M member 7 1 kit
$1,657.00
KN218043 TRPM7 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN218043LP TRPM7 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN218043RB TRPM7 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN418043 TRPM7 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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