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Collagen II (COL2A1) Human Gene Knockout Kit (CRISPR)

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SKU
KN218041BN
COL2A1 - human gene knockout kit via CRISPR, HDR mediated
  $1,657.00
4 Weeks*

Frequently Bought Together (4)

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Other products for "Collagen II or BC007252"

Specifications
Specifications
Product Data
Format 2 gRNA vectors, 1 mBFP-Neo donor, 1 scramble control
Vector mBFP-Neo
Target Symbol Collagen II
Locus ID 1280
Components

KN218041G1, Collagen II gRNA vector 1 in pCas-Guide CRISPR vector

KN218041G2, Collagen II gRNA vector 2 in pCas-Guide CRISPR vector

KN218041BND, donor DNA containing left and right homologous arms and mBFP-Neo functional cassette.

GE100003, scramble sequence in pCas-Guide vector
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq NM_001844, NM_033150
UniProt ID P02458
Synonyms ANFH; AOM; COL11A3; SEDC; STL1
Summary This gene encodes the alpha-1 chain of type II collagen, a fibrillar collagen found in cartilage and the vitreous humor of the eye. Mutations in this gene are associated with achondrogenesis, chondrodysplasia, early onset familial osteoarthritis, SED congenita, Langer-Saldino achondrogenesis, Kniest dysplasia, Stickler syndrome type I, and spondyloepimetaphyseal dysplasia Strudwick type. In addition, defects in processing chondrocalcin, a calcium binding protein that is the C-propeptide of this collagen molecule, are also associated with chondrodysplasia. There are two transcripts identified for this gene. provided by RefSeq, Jul 2008
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Documents
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Other Versions
SKU Description Size Price
GA100895 COL2A1 CRISPRa kit - CRISPR gene activation of human collagen type II alpha 1 chain 1 kit
$1,657.00
KN218041 COL2A1 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN218041LP COL2A1 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN218041RB COL2A1 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN418041 COL2A1 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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