FGF2 Human Gene Knockout Kit (CRISPR)

SKU
KN217426BN
FGF2 - human gene knockout kit via CRISPR, HDR mediated
  $1,657.00
4 Weeks*
Specifications
Specifications
Product Data
Format 2 gRNA vectors, 1 mBFP-Neo donor, 1 scramble control
Vector mBFP-Neo
Target Symbol FGF2
Locus ID 2247
Components

KN217426G1, FGF2 gRNA vector 1 in pCas-Guide CRISPR vector

KN217426G2, FGF2 gRNA vector 2 in pCas-Guide CRISPR vector

KN217426BND, donor DNA containing left and right homologous arms and mBFP-Neo functional cassette.

GE100003, scramble sequence in pCas-Guide vector

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq NM_002006, NM_001361665
UniProt ID P09038
Synonyms BFGF; FGF-2; FGFB; HBGF-2
Summary The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members bind heparin and possess broad mitogenic and angiogenic activities. This protein has been implicated in diverse biological processes, such as limb and nervous system development, wound healing, and tumor growth. The mRNA for this gene contains multiple polyadenylation sites, and is alternatively translated from non-AUG (CUG) and AUG initiation codons, resulting in five different isoforms with distinct properties. The CUG-initiated isoforms are localized in the nucleus and are responsible for the intracrine effect, whereas, the AUG-initiated form is mostly cytosolic and is responsible for the paracrine and autocrine effects of this FGF. provided by RefSeq, Jul 2008
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Other Versions
SKU Description Size Price
GA101570 FGF2 CRISPRa kit - CRISPR gene activation of human fibroblast growth factor 2 1 kit
$1,657.00
KN217426 FGF2 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN217426LP FGF2 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN217426RB FGF2 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN417426 FGF2 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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