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S6K1 (RPS6KB1) Human Gene Knockout Kit (CRISPR)

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SKU
KN217324LP
RPS6KB1 - human gene knockout kit via CRISPR, HDR mediated
  $1,657.00
4 Weeks*

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Other products for "S6K1 or NM_001272042"

Specifications
Specifications
Product Data
Format 2 gRNA vectors, 1 Luciferase-Puro donor, 1 scramble control
Vector Luciferase-Puro
Target Symbol S6K1
Locus ID 6198
Components

KN217324G1, S6K1 gRNA vector 1 in pCas-Guide CRISPR vector

KN217324G2, S6K1 gRNA vector 2 in pCas-Guide CRISPR vector

KN217324LPD, donor DNA containing left and right homologous arms and Luciferase-Puro functional cassette.

GE100003, scramble sequence in pCas-Guide vector
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq NM_001272042, NM_001272043, NM_001272044, NM_001272060, NM_003161, NR_161462, NM_001369670, NM_001369673, NM_001369675, NM_001369677, NM_001369678, NR_161455, NR_161456, NR_161460, NM_001369669, NM_001369671, NM_001369672, NM_001369674, NM_001369676, NM_001369679, NR_161457, NR_161458, NR_161459, NR_161461
UniProt ID P23443
Synonyms p70 S6KA; p70(S6K)-alpha; p70-alpha; p70-S6K; PS6K; S6K; S6K-beta-1; S6K1; STK14A
Summary This gene encodes a member of the ribosomal S6 kinase family of serine/threonine kinases. The encoded protein responds to mTOR (mammalian target of rapamycin) signaling to promote protein synthesis, cell growth, and cell proliferation. Activity of this gene has been associated with human cancer. Alternatively spliced transcript variants have been observed. The use of alternative translation start sites results in isoforms with longer or shorter N-termini which may differ in their subcellular localizations. There are two pseudogenes for this gene on chromosome 17. provided by RefSeq, Jan 2013
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Other Versions
SKU Description Size Price
GA104200 RPS6KB1 CRISPRa kit - CRISPR gene activation of human ribosomal protein S6 kinase B1 1 kit
$1,657.00
KN217324 RPS6KB1 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN217324BN RPS6KB1 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN217324RB RPS6KB1 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN417324 RPS6KB1 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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