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LPHN1 (ADGRL1) Human Gene Knockout Kit (CRISPR)

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SKU
KN217296LP
LPHN1 - human gene knockout kit via CRISPR, HDR mediated
  $1,657.00
4 Weeks*

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Other products for "LPHN1 or NM_001008701"

Specifications
Specifications
Product Data
Format 2 gRNA vectors, 1 Luciferase-Puro donor, 1 scramble control
Vector Luciferase-Puro
Target Symbol LPHN1
Locus ID 22859
Components

KN217296G1, LPHN1 gRNA vector 1 in pCas-Guide CRISPR vector

KN217296G2, LPHN1 gRNA vector 2 in pCas-Guide CRISPR vector

KN217296LPD, donor DNA containing left and right homologous arms and Luciferase-Puro functional cassette.

GE100003, scramble sequence in pCas-Guide vector
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq NM_001008701, NM_014921
UniProt ID O94910
Synonyms CIRL1; CL1; LEC2; LPHN1
Summary This gene encodes a member of the latrophilin subfamily of G-protein coupled receptors (GPCR). Latrophilins may function in both cell adhesion and signal transduction. In experiments with non-human species, endogenous proteolytic cleavage within a cysteine-rich GPS (G-protein-coupled-receptor proteolysis site) domain resulted in two subunits (a large extracellular N-terminal cell adhesion subunit and a subunit with substantial similarity to the secretin/calcitonin family of GPCRs) being non-covalently bound at the cell membrane. Latrophilin-1 has been shown to recruit the neurotoxin from black widow spider venom, alpha-latrotoxin, to the synapse plasma membrane. Alternative splicing results in multiple variants encoding distinct isoforms.provided by RefSeq, Oct 2008
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Other Versions
SKU Description Size Price
GA107859 ADGRL1 CRISPRa kit - CRISPR gene activation of human adhesion G protein-coupled receptor L1 1 kit
$1,657.00
KN217296 ADGRL1 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN217296BN LPHN1 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN217296RB LPHN1 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN417296 ADGRL1 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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