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Parkin (PARK2) Human Gene Knockout Kit (CRISPR)

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SKU
KN216186RB
PARK2 - human gene knockout kit via CRISPR, HDR mediated
  $1,657.00
4 Weeks*

Frequently Bought Together (4)

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RC216186 PARK2 (Myc-DDK-tagged)-Human parkinson protein 2, E3 ubiquitin protein ligase (parkin) (PARK2), transcript variant 3
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GE100003 pCAS-Scramble, pCas-Guide vector with a scrambled sequence as a negative control (10 µg)
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Other products for "Parkin or BC022014"

Specifications
Specifications
Product Data
Format 2 gRNA vectors, 1 RFP-BSD donor, 1 scramble control
Vector RFP-BSD
Target Symbol Parkin
Locus ID 5071
Components

KN216186G1, Parkin gRNA vector 1 in pCas-Guide CRISPR vector

KN216186G2, Parkin gRNA vector 2 in pCas-Guide CRISPR vector

KN216186RBD, donor DNA containing left and right homologous arms and RFP-BSD functional cassette.

GE100003, scramble sequence in pCas-Guide vector
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq NM_004562, NM_013987, NM_013988
UniProt ID O60260
Synonyms AR-JP; LPRS2; PDJ; PRKN
Summary The precise function of this gene is unknown; however, the encoded protein is a component of a multiprotein E3 ubiquitin ligase complex that mediates the targeting of substrate proteins for proteasomal degradation. Mutations in this gene are known to cause Parkinson disease and autosomal recessive juvenile Parkinson disease. Alternative splicing of this gene produces multiple transcript variants encoding distinct isoforms. Additional splice variants of this gene have been described but currently lack transcript support. provided by RefSeq, Jul 2008
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Documents
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Other Versions
SKU Description Size Price
GA103386 PRKN CRISPRa kit - CRISPR gene activation of human parkin RBR E3 ubiquitin protein ligase 1 kit
$1,657.00
KN216186 PARK2 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN216186BN PARK2 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN216186LP PARK2 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN416186 PARK2 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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