SLC39A6 Human Gene Knockout Kit (CRISPR)

SKU KN216107BN

SLC39A6 - human gene knockout kit via CRISPR, HDR mediated

Product Data

• Format: 2 gRNA vectors, 1 mBFP-Neo donor, 1 scramble control
• Vector: mBFP-Neo
• Target Symbol: SLC39A6
• Locus ID: 25800
• Components:

  KN216107G1, SLC39A6 gRNA vector 1 in pCas-Guide CRISPR vector

  KN216107G2, SLC39A6 gRNA vector 2 in pCas-Guide CRISPR vector

  KN216107BND, donor DNA containing left and right homologous arms and mBFP-Neo functional cassette.

  GE100003, scramble sequence in pCas-Guide vector

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.

Reference Data

• RefSeq: NM_001099406, NM_012319
• UniProt ID: Q13433
• Synonyms: LIV-1; ZIP6
• Summary: Zinc is an essential cofactor for hundreds of enzymes. It is involved in protein, nucleic acid, carbohydrate, and lipid metabolism, as well as in the control of gene transcription, growth, development, and differentiation. SLC39A6 belongs to a subfamily of proteins that show structural characteristics of zinc transporters (Taylor and Nicholson, 2003 [PubMed 12659941]).[supplied by OMIM, Mar 2008]
• Shipping: Ambient