HCFC1 Human Gene Knockout Kit (CRISPR)
Specifications
| Product Data | |
| Format | 2 gRNA vectors, 1 mBFP-Neo donor, 1 scramble control |
|---|---|
| Vector | mBFP-Neo |
| Target Symbol | HCFC1 |
| Locus ID | 3054 |
| Components |
KN215341G1, HCFC1 gRNA vector 1 in pCas-Guide CRISPR vector KN215341G2, HCFC1 gRNA vector 2 in pCas-Guide CRISPR vector KN215341BND, donor DNA containing left and right homologous arms and mBFP-Neo functional cassette. GE100003, scramble sequence in pCas-Guide vector |
| OTI Disclaimer | These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process. |
| Reference Data | |
| RefSeq | NM_005334 |
| UniProt ID | P51610 |
| Synonyms | CFF; HCF; HCF-1; HCF1; HFC1; MRX3; PPP1R89; VCAF |
| Summary | This gene is a member of the host cell factor family and encodes a protein with five Kelch repeats, a fibronectin-like motif, and six HCF repeats, each of which contains a highly specific cleavage signal. This nuclear coactivator is proteolytically cleaved at one of the six possible sites, resulting in the creation of an N-terminal chain and the corresponding C-terminal chain. The final form of this protein consists of noncovalently bound N- and C-terminal chains. The protein is involved in control of the cell cycle and transcriptional regulation during herpes simplex virus infection. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized. provided by RefSeq, Jul 2008 |
| Shipping | Ambient |
Reviews
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Resources
Other Versions
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| GA102081 | HCFC1 CRISPRa kit - CRISPR gene activation of human host cell factor C1 | 1 kit |
$1,657.00
|
|
| KN215341 | HCFC1 - human gene knockout kit via CRISPR, HDR mediated | 1 kit |
$1,657.00
|
|
| KN215341LP | HCFC1 - human gene knockout kit via CRISPR, HDR mediated | 1 kit |
$1,657.00
|
|
| KN215341RB | HCFC1 - human gene knockout kit via CRISPR, HDR mediated | 1 kit |
$1,657.00
|
|
| KN415341 | HCFC1 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. | 1 kit |
$1,657.00
|
|
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