Stella (DPPA3) Human Gene Knockout Kit (CRISPR)

SKU KN214676LP

DPPA3 - human gene knockout kit via CRISPR, HDR mediated

Product Data

• Format: 2 gRNA vectors, 1 Luciferase-Puro donor, 1 scramble control
• Vector: Luciferase-Puro
• Target Symbol: Stella
• Locus ID: 359787
• Components:

  KN214676G1, Stella gRNA vector 1 in pCas-Guide CRISPR vector

  KN214676G2, Stella gRNA vector 2 in pCas-Guide CRISPR vector

  KN214676LPD, donor DNA containing left and right homologous arms and Luciferase-Puro functional cassette.

  GE100003, scramble sequence in pCas-Guide vector

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.

Reference Data

• RefSeq: NM_199286
• UniProt ID: Q6W0C5
• Synonyms: STELLA
• Summary: This gene encodes a protein that in mice may function as a maternal factor during the preimplantation stage of development. In mice, this gene may play a role in transcriptional repression, cell division, and maintenance of cell pluripotentiality. In humans, related intronless loci are located on chromosomes 14 and X. [provided by RefSeq, Jul 2008]
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