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RIZ1 (PRDM2) Human Gene Knockout Kit (CRISPR)

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SKU
KN214550BN
PRDM2 - human gene knockout kit via CRISPR, HDR mediated
  $1,657.00
4 Weeks*

Frequently Bought Together (3)

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Other products for "RIZ1 or NM_001007257"

Specifications
Specifications
Product Data
Format 2 gRNA vectors, 1 mBFP-Neo donor, 1 scramble control
Vector mBFP-Neo
Target Symbol RIZ1
Locus ID 7799
Components

KN214550G1, RIZ1 gRNA vector 1 in pCas-Guide CRISPR vector

KN214550G2, RIZ1 gRNA vector 2 in pCas-Guide CRISPR vector

KN214550BND, donor DNA containing left and right homologous arms and mBFP-Neo functional cassette.

GE100003, scramble sequence in pCas-Guide vector
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq NM_001007257, NM_001135610, NM_012231, NM_015866
UniProt ID Q13029
Synonyms HUMHOXY1; KMT8; MTB-ZF; RIZ; RIZ1; RIZ2
Summary This tumor suppressor gene is a member of a nuclear histone/protein methyltransferase superfamily. It encodes a zinc finger protein that can bind to retinoblastoma protein, estrogen receptor, and the TPA-responsive element (MTE) of the heme-oxygenase-1 gene. Although the functions of this protein have not been fully characterized, it may (1) play a role in transcriptional regulation during neuronal differentiation and pathogenesis of retinoblastoma, (2) act as a transcriptional activator of the heme-oxygenase-1 gene, and (3) be a specific effector of estrogen action. Multiple transcript variants encoding different isoforms have been found for this gene. provided by RefSeq, Oct 2008
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Documents
Resources
Other Versions
SKU Description Size Price
GA105318 PRDM2 CRISPRa kit - CRISPR gene activation of human PR/SET domain 2 1 kit
$1,657.00
KN214550 PRDM2 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN214550LP PRDM2 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN214550RB PRDM2 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN414550 PRDM2 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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