Human RIZ1 (PRDM2) activation kit by CRISPRa

SKU
GA105318
PRDM2 CRISPRa kit - CRISPR gene activation of human PR/SET domain 2
  $1,657.00
4 Weeks*
Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol PRDM2
Locus ID 7799
Components

GA105318G1, RIZ1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA105318G2, RIZ1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA105318G3, RIZ1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_001007257, NM_001135610, NM_012231, NM_015866
UniProt ID Q13029
Synonyms HUMHOXY1; KMT8; MTB-ZF; RIZ; RIZ1; RIZ2
Summary This tumor suppressor gene is a member of a nuclear histone/protein methyltransferase superfamily. It encodes a zinc finger protein that can bind to retinoblastoma protein, estrogen receptor, and the TPA-responsive element (MTE) of the heme-oxygenase-1 gene. Although the functions of this protein have not been fully characterized, it may (1) play a role in transcriptional regulation during neuronal differentiation and pathogenesis of retinoblastoma, (2) act as a transcriptional activator of the heme-oxygenase-1 gene, and (3) be a specific effector of estrogen action. Multiple transcript variants encoding different isoforms have been found for this gene. provided by RefSeq, Oct 2008
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Documents
Resources
Other Versions
SKU Description Size Price
KN214550 PRDM2 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN214550BN PRDM2 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN214550LP PRDM2 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN214550RB PRDM2 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN414550 PRDM2 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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