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COL27A1 Human Gene Knockout Kit (CRISPR)

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SKU
KN214474RB
COL27A1 - human gene knockout kit via CRISPR, HDR mediated
  $1,657.00
4 Weeks*

Frequently Bought Together (4)

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Other products for "COL27A1 or NM_032161"

Specifications
Specifications
Product Data
Format 2 gRNA vectors, 1 RFP-BSD donor, 1 scramble control
Vector RFP-BSD
Target Symbol COL27A1
Locus ID 85301
Components

KN214474G1, COL27A1 gRNA vector 1 in pCas-Guide CRISPR vector

KN214474G2, COL27A1 gRNA vector 2 in pCas-Guide CRISPR vector

KN214474RBD, donor DNA containing left and right homologous arms and RFP-BSD functional cassette.

GE100003, scramble sequence in pCas-Guide vector
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq NM_032161, NM_032888
UniProt ID Q8IZC6
Synonyms STLS
Summary This gene encodes a member of the fibrillar collagen family, and plays a role during the calcification of cartilage and the transition of cartilage to bone. The encoded protein product is a preproprotein. It includes an N-terminal signal peptide, which is followed by an N-terminal propetide, mature peptide and a C-terminal propeptide. The N-terminal propeptide contains thrombospondin N-terminal-like and laminin G-like domains. The mature peptide is a major triple-helical region. The C-terminal propeptide, also known as COLFI domain, plays crucial roles in tissue growth and repair. Mutations in this gene cause Steel syndrome. Alternatively spliced transcript variants have been found, but the full-length nature of some variants has not been determined. provided by RefSeq, Sep 2014
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Other Versions
SKU Description Size Price
GA113845 COL27A1 CRISPRa kit - CRISPR gene activation of human collagen type XXVII alpha 1 chain 1 kit
$1,657.00
KN214474 COL27A1 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN214474BN COL27A1 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN214474LP COL27A1 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN414474 COL27A1 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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