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PTPRU Human Gene Knockout Kit (CRISPR)

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SKU
KN214198RB
PTPRU - human gene knockout kit via CRISPR, HDR mediated
  $1,657.00
4 Weeks*

Frequently Bought Together (3)

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Other products for "PTPRU or NM_001195001"

Specifications
Specifications
Product Data
Format 2 gRNA vectors, 1 RFP-BSD donor, 1 scramble control
Vector RFP-BSD
Target Symbol PTPRU
Locus ID 10076
Components

KN214198G1, PTPRU gRNA vector 1 in pCas-Guide CRISPR vector

KN214198G2, PTPRU gRNA vector 2 in pCas-Guide CRISPR vector

KN214198RBD, donor DNA containing left and right homologous arms and RFP-BSD functional cassette.

GE100003, scramble sequence in pCas-Guide vector
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq NM_001195001, NM_005704, NM_133177, NM_133178
UniProt ID Q92729
Synonyms FMI; hPTP-J; PCP-2; PTP; PTP-J; PTP-PI; PTP-RO; PTPPSI; PTPRO; PTPU2; R-PTP-PSI; R-PTP-U
Summary The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and two tandem intracellular catalytic domains, and thus represents a receptor-type PTP. The extracellular region contains a meprin-A5 antigen-PTP (MAM) domain, Ig-like and fibronectin type III-like repeats. This PTP was thought to play roles in cell-cell recognition and adhesion. Studies of the similar gene in mice suggested the role of this PTP in early neural development. The expression of this gene was reported to be regulated by phorbol myristate acetate (PMA) or calcium ionophore in Jurkat T lymphoma cells. Alternatively spliced transcript variants have been reported. provided by RefSeq, Aug 2010
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Documents
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Other Versions
SKU Description Size Price
GA106829 PTPRU CRISPRa kit - CRISPR gene activation of human protein tyrosine phosphatase receptor type U 1 kit
$1,657.00
KN214198 PTPRU - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN214198BN PTPRU - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN214198LP PTPRU - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN414198 PTPRU - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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