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DROSHA Human Gene Knockout Kit (CRISPR)

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SKU
KN213916LP
DROSHA - human gene knockout kit via CRISPR, HDR mediated
  $1,657.00
4 Weeks*

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Other products for "DROSHA or NM_001100412"

Specifications
Specifications
Product Data
Format 2 gRNA vectors, 1 Luciferase-Puro donor, 1 scramble control
Vector Luciferase-Puro
Target Symbol DROSHA
Locus ID 29102
Components

KN213916G1, DROSHA gRNA vector 1 in pCas-Guide CRISPR vector

KN213916G2, DROSHA gRNA vector 2 in pCas-Guide CRISPR vector

KN213916LPD, donor DNA containing left and right homologous arms and Luciferase-Puro functional cassette.

GE100003, scramble sequence in pCas-Guide vector
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq NM_001100412, NM_013235
UniProt ID Q9NRR4
Synonyms ETOHI2; HSA242976; RANSE3L; RN3; RNASE3L; RNASEN
Summary This gene encodes a ribonuclease (RNase) III double-stranded RNA-specific ribonuclease and subunit of the microprocessor protein complex, which catalyzes the initial processing step of microRNA (miRNA) synthesis. The encoded protein cleaves the stem loop structure from the primary microRNA (pri-miRNA) in the nucleus, yielding the precursor miRNA (pre-miRNA), which is then exported to the cytoplasm for further processing. In a human cell line lacking a functional copy of this gene, canonical miRNA synthesis is reduced. Somatic mutations in this gene have been observed in human patients with kidney cancer. provided by RefSeq, Sep 2016
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Documents
Resources
Other Versions
SKU Description Size Price
GA109235 DROSHA CRISPRa kit - CRISPR gene activation of human drosha ribonuclease III 1 kit
$1,657.00
KN213916 DROSHA - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN213916BN DROSHA - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN213916RB DROSHA - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN413916 DROSHA - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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