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Human DROSHA activation kit by CRISPRa

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SKU
GA109235
DROSHA CRISPRa kit - CRISPR gene activation of human drosha ribonuclease III
  $1,657.00
4 Weeks*

Frequently Bought Together (2)

TA368205 DROSHA rabbit polyclonal antibody
100 ul
$310.00
RC213916 DROSHA (Myc-DDK-tagged)-Human drosha, ribonuclease type III (DROSHA), transcript variant 1
10 ug
$1,763.00

Other products for "DROSHA"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol DROSHA
Locus ID 29102
Components

GA109235G1, DROSHA gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA109235G2, DROSHA gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA109235G3, DROSHA gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_001100412, NM_013235
UniProt ID Q9NRR4
Synonyms ETOHI2; HSA242976; RANSE3L; RN3; RNASE3L; RNASEN
Summary This gene encodes a ribonuclease (RNase) III double-stranded RNA-specific ribonuclease and subunit of the microprocessor protein complex, which catalyzes the initial processing step of microRNA (miRNA) synthesis. The encoded protein cleaves the stem loop structure from the primary microRNA (pri-miRNA) in the nucleus, yielding the precursor miRNA (pre-miRNA), which is then exported to the cytoplasm for further processing. In a human cell line lacking a functional copy of this gene, canonical miRNA synthesis is reduced. Somatic mutations in this gene have been observed in human patients with kidney cancer. provided by RefSeq, Sep 2016
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Documents
Resources
Other Versions
SKU Description Size Price
KN213916 DROSHA - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN213916BN DROSHA - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN213916LP DROSHA - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN213916RB DROSHA - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN413916 DROSHA - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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