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PAK1 Human Gene Knockout Kit (CRISPR)

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SKU
KN213831RB
PAK1 - human gene knockout kit via CRISPR, HDR mediated
  $1,657.00
4 Weeks*

Frequently Bought Together (3)

RC225947 PAK1 (Myc-DDK-tagged)-Human p21 protein (Cdc42/Rac)-activated kinase 1 (PAK1), transcript variant 1
10 ug
$772.00
GE100003 pCAS-Scramble, pCas-Guide vector with a scrambled sequence as a negative control (10 µg)
10 ug
$470.00
TT300007S A non-viral, non-electroporation, non-liposomal transfection kit using engineered mammalian proteins, tailored for high-efficiency delivery into a wide range of primary cells and difficult to transfect cell lines such as immune cells, stem cells, and neuronal cells.
20 ul
$265.00

Other products for "PAK1 or NM_001128620"

Specifications
Specifications
Product Data
Format 2 gRNA vectors, 1 RFP-BSD donor, 1 scramble control
Vector RFP-BSD
Target Symbol PAK1
Locus ID 5058
Components

KN213831G1, PAK1 gRNA vector 1 in pCas-Guide CRISPR vector

KN213831G2, PAK1 gRNA vector 2 in pCas-Guide CRISPR vector

KN213831RBD, donor DNA containing left and right homologous arms and RFP-BSD functional cassette.

GE100003, scramble sequence in pCas-Guide vector
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq NM_001128620, NM_002576
UniProt ID Q13153
Synonyms PAKalpha
Summary This gene encodes a family member of serine/threonine p21-activating kinases, known as PAK proteins. These proteins are critical effectors that link RhoGTPases to cytoskeleton reorganization and nuclear signaling, and they serve as targets for the small GTP binding proteins Cdc42 and Rac. This specific family member regulates cell motility and morphology. Mutations in this gene have been associated with macrocephaly, seizures, and speech delay. Overexpression of this gene is also reported in many cancer types, and particularly in breast cancer. Alternative splicing results in multiple transcript variants. provided by RefSeq, Aug 2020
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Other Versions
SKU Description Size Price
GA103378 PAK1 CRISPRa kit - CRISPR gene activation of human p21 (RAC1) activated kinase 1 1 kit
$1,657.00
KN213831 PAK1 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN213831BN PAK1 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN213831LP PAK1 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN413831 PAK1 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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