PARP2 Human Gene Knockout Kit (CRISPR)
Specifications
| Product Data | |
| Format | 2 gRNA vectors, 1 Luciferase-Puro donor, 1 scramble control |
|---|---|
| Vector | Luciferase-Puro |
| Target Symbol | PARP2 |
| Locus ID | 10038 |
| Components |
KN213586G1, PARP2 gRNA vector 1 in pCas-Guide CRISPR vector KN213586G2, PARP2 gRNA vector 2 in pCas-Guide CRISPR vector KN213586LPD, donor DNA containing left and right homologous arms and Luciferase-Puro functional cassette. GE100003, scramble sequence in pCas-Guide vector |
| OTI Disclaimer | These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process. |
| Reference Data | |
| RefSeq | NM_001042618, NM_005484 |
| UniProt ID | Q9UGN5 |
| Synonyms | ADPRT2; ADPRTL2; ADPRTL3; ARTD2; pADPRT-2; PARP-2 |
| Summary | This gene encodes poly(ADP-ribosyl)transferase-like 2 protein, which contains a catalytic domain and is capable of catalyzing a poly(ADP-ribosyl)ation reaction. This protein has a catalytic domain which is homologous to that of poly (ADP-ribosyl) transferase, but lacks an N-terminal DNA binding domain which activates the C-terminal catalytic domain of poly (ADP-ribosyl) transferase. The basic residues within the N-terminal region of this protein may bear potential DNA-binding properties, and may be involved in the nuclear and/or nucleolar targeting of the protein. Two alternatively spliced transcript variants encoding distinct isoforms have been found. provided by RefSeq, Jul 2008 |
| Shipping | Ambient |
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Other Versions
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| GA106796 | PARP2 CRISPRa kit - CRISPR gene activation of human poly(ADP-ribose) polymerase 2 | 1 kit |
$1,657.00
|
|
| KN213586 | PARP2 - human gene knockout kit via CRISPR, HDR mediated | 1 kit |
$1,657.00
|
|
| KN213586BN | PARP2 - human gene knockout kit via CRISPR, HDR mediated | 1 kit |
$1,657.00
|
|
| KN213586RB | PARP2 - human gene knockout kit via CRISPR, HDR mediated | 1 kit |
$1,657.00
|
|
| KN413586 | PARP2 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. | 1 kit |
$1,657.00
|
|
Citations
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