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NCoR (NCOR1) Human Gene Knockout Kit (CRISPR)

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SKU
KN213467RB
NCOR1 - human gene knockout kit via CRISPR, HDR mediated
  $1,657.00
4 Weeks*

Frequently Bought Together (3)

RC213467 NCOR1 (Myc-DDK-tagged)-Human nuclear receptor corepressor 1 (NCOR1), transcript variant 1
10 ug
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TT300007S A non-viral, non-electroporation, non-liposomal transfection kit using engineered mammalian proteins, tailored for high-efficiency delivery into a wide range of primary cells and difficult to transfect cell lines such as immune cells, stem cells, and neuronal cells.
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Other products for "NCoR or NM_001190438"

Specifications
Specifications
Product Data
Format 2 gRNA vectors, 1 RFP-BSD donor, 1 scramble control
Vector RFP-BSD
Target Symbol NCoR
Locus ID 9611
Components

KN213467G1, NCoR gRNA vector 1 in pCas-Guide CRISPR vector

KN213467G2, NCoR gRNA vector 2 in pCas-Guide CRISPR vector

KN213467RBD, donor DNA containing left and right homologous arms and RFP-BSD functional cassette.

GE100003, scramble sequence in pCas-Guide vector
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq NM_001190438, NM_001190440, NM_006311
UniProt ID O75376
Synonyms hN-CoR; N-CoR; N-CoR1; PPP1R109; TRAC1
Summary This gene encodes a protein that mediates ligand-independent transcription repression of thyroid-hormone and retinoic-acid receptors by promoting chromatin condensation and preventing access of the transcription machinery. It is part of a complex which also includes histone deacetylases and transcriptional regulators similar to the yeast protein Sin3p. This gene is located between the Charcot-Marie-Tooth and Smith-Magenis syndrome critical regions on chromosome 17. Alternate splicing results in multiple transcript variants. Pseudogenes of this gene are found on chromosomes 17 and 20.provided by RefSeq, Jun 2010
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Other Versions
SKU Description Size Price
GA106435 NCOR1 CRISPRa kit - CRISPR gene activation of human nuclear receptor corepressor 1 1 kit
$1,657.00
KN213467 NCOR1 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN213467BN NCOR1 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN213467LP NCOR1 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN413467 NCOR1 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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