OGR1 (GPR68) Human Gene Knockout Kit (CRISPR)

CAT#: KN212925RB

GPR68 - human gene knockout kit via CRISPR, HDR mediated

Product Images

Specifications

Product Data

• Format: 2 gRNA vectors, 1 RFP-BSD donor, 1 scramble control
• Donor DNA: RFP-BSD
• Symbol: OGR1
• Locus ID: 8111
• Components:

  KN212925G1, OGR1 gRNA vector 1 in pCas-Guide CRISPR vector

  KN212925G2, OGR1 gRNA vector 2 in pCas-Guide CRISPR vector

  KN212925RBD, donor DNA containing left and right homologous arms and RFP-BSD functional cassette.

  GE100003, scramble sequence in pCas-Guide vector

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.

Reference Data

• RefSeq: NM_001177676, NM_003485, NM_001348437
• UniProt ID: Q15743
• Synonyms: GPR12A; OGR1
• Summary: The protein encoded by this gene is a G protein-coupled receptor for sphingosylphosphorylcholine. The encoded protein is a proton-sensing receptor, inactive at pH 7.8 but active at pH 6.8. Mutations in this gene are a cause of amelogenesis imperfecta. [provided by RefSeq, Feb 2017]