LYN Human Gene Knockout Kit (CRISPR)

SKU KN212851BN

LYN - human gene knockout kit via CRISPR, HDR mediated

Product Data

• Format: 2 gRNA vectors, 1 mBFP-Neo donor, 1 scramble control
• Vector: mBFP-Neo
• Target Symbol: LYN
• Locus ID: 4067
• Components:

  KN212851G1, LYN gRNA vector 1 in pCas-Guide CRISPR vector

  KN212851G2, LYN gRNA vector 2 in pCas-Guide CRISPR vector

  KN212851BND, donor DNA containing left and right homologous arms and mBFP-Neo functional cassette.

  GE100003, scramble sequence in pCas-Guide vector

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.

Reference Data

• RefSeq: NM_001111097, NM_002350
• UniProt ID: P07948
• Synonyms: JTK8; p53Lyn; p56Lyn
• Summary: This gene encodes a tyrosine protein kinase, which maybe involved in the regulation of mast cell degranulation, and erythroid differentiation. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2011]
• Shipping: Ambient