RON (MST1R) Human Gene Knockout Kit (CRISPR)

SKU
KN212786RB
MST1R - human gene knockout kit via CRISPR, HDR mediated
  $1,657.00
4 Weeks*
Specifications
Specifications
Product Data
Format 2 gRNA vectors, 1 RFP-BSD donor, 1 scramble control
Vector RFP-BSD
Target Symbol RON
Locus ID 4486
Components

KN212786G1, RON gRNA vector 1 in pCas-Guide CRISPR vector

KN212786G2, RON gRNA vector 2 in pCas-Guide CRISPR vector

KN212786RBD, donor DNA containing left and right homologous arms and RFP-BSD functional cassette.

GE100003, scramble sequence in pCas-Guide vector

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq NM_001244937, NM_001318913, NM_002447, NR_134919
UniProt ID Q04912
Synonyms CD136; CDw136; PTK8; RON
Summary This gene encodes a cell surface receptor for macrophage-stimulating protein (MSP) with tyrosine kinase activity. The mature form of this protein is a heterodimer of disulfide-linked alpha and beta subunits, generated by proteolytic cleavage of a single-chain precursor. The beta subunit undergoes tyrosine phosphorylation upon stimulation by MSP. This protein is expressed on the ciliated epithelia of the mucociliary transport apparatus of the lung, and together with MSP, thought to be involved in host defense. Alternative splicing generates multiple transcript variants encoding different isoforms that may undergo similar proteolytic processing. provided by RefSeq, Jan 2016
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Other Versions
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GA102991 MST1R CRISPRa kit - CRISPR gene activation of human macrophage stimulating 1 receptor 1 kit
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KN212786 MST1R - human gene knockout kit via CRISPR, HDR mediated 1 kit
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KN212786BN MST1R - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN212786LP MST1R - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN412786 MST1R - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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