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Collagen V (COL5A1) Human Gene Knockout Kit (CRISPR)

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SKU
KN212443LP
COL5A1 - human gene knockout kit via CRISPR, HDR mediated
  $1,657.00
4 Weeks*

Frequently Bought Together (4)

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Other products for "Collagen V or NM_000093"

Specifications
Specifications
Product Data
Format 2 gRNA vectors, 1 Luciferase-Puro donor, 1 scramble control
Vector Luciferase-Puro
Target Symbol Collagen V
Locus ID 1289
Components

KN212443G1, Collagen V gRNA vector 1 in pCas-Guide CRISPR vector

KN212443G2, Collagen V gRNA vector 2 in pCas-Guide CRISPR vector

KN212443LPD, donor DNA containing left and right homologous arms and Luciferase-Puro functional cassette.

GE100003, scramble sequence in pCas-Guide vector
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq NM_000093, NM_001278074
UniProt ID P20908
Synonyms alpha 1 type V collagen; collagen, type V, alpha 1; OTTHUMP00000022513; OTTHUMP00000064637
Summary This gene encodes an alpha chain for one of the low abundance fibrillar collagens. Fibrillar collagen molecules are trimers that can be composed of one or more types of alpha chains. Type V collagen is found in tissues containing type I collagen and appears to regulate the assembly of heterotypic fibers composed of both type I and type V collagen. This gene product is closely related to type XI collagen and it is possible that the collagen chains of types V and XI constitute a single collagen type with tissue-specific chain combinations. The encoded procollagen protein occurs commonly as the heterotrimer pro-alpha1(V)-pro-alpha1(V)-pro-alpha2(V). Mutations in this gene are associated with Ehlers-Danlos syndrome, types I and II. Alternative splicing of this gene results in multiple transcript variants. provided by RefSeq, May 2013
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Documents
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Other Versions
SKU Description Size Price
GA100903 COL5A1 CRISPRa kit - CRISPR gene activation of human collagen type V alpha 1 chain 1 kit
$1,657.00
KN212443 COL5A1 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN212443BN COL5A1 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN212443RB COL5A1 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN412443 COL5A1 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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