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DEPDC5 Human Gene Knockout Kit (CRISPR)

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SKU
KN211462BN
DEPDC5 - human gene knockout kit via CRISPR, HDR mediated
  $1,657.00
4 Weeks*

Frequently Bought Together (3)

RC211462 DEPDC5 (Myc-DDK-tagged)-Human DEP domain containing 5 (DEPDC5), transcript variant 2
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Other products for "DEPDC5 or NM_001007188"

Specifications
Specifications
Product Data
Format 2 gRNA vectors, 1 mBFP-Neo donor, 1 scramble control
Vector mBFP-Neo
Target Symbol DEPDC5
Locus ID 9681
Components

KN211462G1, DEPDC5 gRNA vector 1 in pCas-Guide CRISPR vector

KN211462G2, DEPDC5 gRNA vector 2 in pCas-Guide CRISPR vector

KN211462BND, donor DNA containing left and right homologous arms and mBFP-Neo functional cassette.

GE100003, scramble sequence in pCas-Guide vector
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq NM_001007188, NM_001136029, NM_001242896, NM_001242897, NM_014662, NR_110988, NR_146296, NM_001364318, NM_001364320, NM_001369902, NM_001369903, NR_157126, NR_157128, NM_001363852, NM_001363854, NM_001364319, NM_001369901, NR_157125
UniProt ID O75140
Synonyms DEP.5; FFEVF
Summary This gene encodes a member of the IML1 family of proteins involved in G-protein signaling pathways. The mechanistic target of rapamycin complex 1 (mTORC1) pathway regulates cell growth by sensing the availability of nutrients. The protein encoded by this gene is a component of the GATOR1 (GAP activity toward Rags) complex which inhibits the amino acid-sensing branch of the mTORC1 pathway. Mutations in this gene are associated with autosomal dominant familial focal epilepsy with variable foci. A single nucleotide polymorphism in an intron of this gene has been associated with an increased risk of hepatocellular carcinoma in individuals with chronic hepatitis C virus infection. Alternative splicing results in multiple transcript variants. provided by RefSeq, Mar 2014
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Documents
Resources
Other Versions
SKU Description Size Price
GA106493 DEPDC5 CRISPRa kit - CRISPR gene activation of human DEP domain containing 5 1 kit
$1,657.00
KN211462 DEPDC5 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN211462LP DEPDC5 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN211462RB DEPDC5 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN411462 DEPDC5 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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