Tyrosine Hydroxylase (TH) Human Gene Knockout Kit (CRISPR)

SKU
KN211218LP
TH - human gene knockout kit via CRISPR, HDR mediated
  $1,657.00
4 Weeks*
Specifications
Specifications
Product Data
Format 2 gRNA vectors, 1 Luciferase-Puro donor, 1 scramble control
Vector Luciferase-Puro
Target Symbol Tyrosine Hydroxylase
Locus ID 7054
Components

KN211218G1, Tyrosine Hydroxylase gRNA vector 1 in pCas-Guide CRISPR vector

KN211218G2, Tyrosine Hydroxylase gRNA vector 2 in pCas-Guide CRISPR vector

KN211218LPD, donor DNA containing left and right homologous arms and Luciferase-Puro functional cassette.

GE100003, scramble sequence in pCas-Guide vector

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq NM_000360, NM_199292, NM_199293
UniProt ID P07101
Synonyms DYT5b; DYT14; TYH
Summary The protein encoded by this gene is involved in the conversion of tyrosine to dopamine. It is the rate-limiting enzyme in the synthesis of catecholamines, hence plays a key role in the physiology of adrenergic neurons. Mutations in this gene have been associated with autosomal recessive Segawa syndrome. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene. provided by RefSeq, Jul 2008
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Other Versions
SKU Description Size Price
GA104861 TH CRISPRa kit - CRISPR gene activation of human tyrosine hydroxylase 1 kit
$1,657.00
KN211218 TH - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN211218BN TH - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN211218RB TH - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN411218 TH - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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